I've been on and off many different AD medications for the last 25-30 years. I just wanted to say that I also respond very quickly to a new med. The Doc always says 6 weeks to build up a blood level to get a good response. I always felt significant benefits by the end of the first week. Also, there have been a few over the years that worked much better at a lower dose than the 'regular' dose. Fighting depression is life long for some and more short term for others, but the battle is always worth it as life can be less painful and actually 'fun' and enjoyable again. Keep up the good fight and remember you are dealing with a disease, not a character flaw!