That's a really good point, Speakermom. A few years ago my doctor put me on anti-depressants. I started on Wellbutrin, but eventually decided it wasn't working for me. So I switched to Effexor. That worked better for me. But the one thing it wouldn't fix was the extreme fatigue...the doctor hadn't bothered to investigate beyond the "depression" diagnosis (which is often the case), but I asked her to delve deeper, and she finally discovered I was "dangerously low" in B12 and had an elevated white blood count. So in addition to the AD's, I started taking a B-complex every day. Within a few days the extreme fatigue eased enough to allow me to climb stairs and do basic stuff around the house.

As for the elevated white-blood count, by testing me when I was feeling good as well as when I was feeling worse, we managed to uncover a direct correlation between the extreme fatigue and the higher WBC. We never did find out what was behind the WBC, but it lasted for about two years. (I found out much later, while talking with my brother's hemotologist in the hospital last February, that such a high WBC should have been thoroughly investigated)

Anyway, these days I have significantly more energy - and both my WBC and B12 counts are normal. So there might be more to your story than depression. Make sure you get some blood work done to rule out other factors...B12 deficiency is much more common than you would think, and does contribute to fatigue and depression.
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When you don't like a thing, change it.
If you can't change it, change the way you think about it.

(Maya Angelou)