I take a multi-vit & min called Life's Fortune (very potent - I can only take one a day and sometimes I have to skip a day), along with Vit C, Vit E, FishOil, l-Lysine, Biotin and HSN, CQ10. I was taking glucosamine and chondroitin sulfate, on my sister's recommendation, but once my supply ran out, I gave it up. Didn't find that it made a difference.