The best thing is NOT to carry anything that is liquid or things like scissors or nail clippers on board in your carry on. My last trip, I did that and it worked out better for me in the long run. Less to carry. If you can go without a carry on you are better off. I tried but couldn't do it. I did use a much smaller one though. Keep all meds with you, not in checked luggage and make sure you have prescription drugs in the bottles with your name on them.

Louisa