I love my eReader, but another thing I found isn't so convenient on it is a language dictionary (eg, my Spanish dictionary), because I can't easily flip open to relevant sections to check a word or phrase. But as Mary Anne says, for fiction, when you're reading something cover-to-cover, it's wonderful. I've been taking mine to all the medical appts lately and it's so convenient.
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When you don't like a thing, change it.
If you can't change it, change the way you think about it.

(Maya Angelou)