I've been doing a good deal of research on hormones and recommend that everyone check into Dr. John Lee's book "What your Doctor didn't tell you about Menopause" You can find his link and read a few pages. I started using progesterone cream and made an ovarian cyst disappear, another one shrink, and am working on destroying my uterine fibroids. Lee says the worst thing is the unopposed estrogen. Along with the cream, I'm only eating hormone free meat & dairy and organic produce -- according to Lee and others, many of the pesticides behave like estrogens. I got very angry when I realized all this, thus adopted this radical diet. but I feel great -- no more cramps, no more flooding, no more insomnia! For me this has happened after 3 months of the cream.