I'm 52, not in menopause quite yet. Up 2-3 times at night. It's been going on for about 2 yrs. I read that it is part of the aging process & doc agrees after tests during annual physical. But I feel it interferes with sleep and that interferes with moods and health during the day. It is much, much better if I don't drink much water or anything in the evening. Cutting out caffein in the afternoons and evening really helps. So does watching salt intake. I really need that quality sleep and don't like to take anything.